Amynah A Pradhan Selected Research

Nitroglycerin (Dynamite)

1/2022	Migraine and peripheral pain models show differential alterations in neuronal complexity.
1/2021	Delta opioid receptor regulation of calcitonin gene-related peptide dynamics in the trigeminal complex.
1/2021	Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition.
1/2021	A non-convulsant delta-opioid receptor agonist, KNT-127, reduces cortical spreading depression and nitroglycerin-induced allodynia.
10/2020	Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia.
1/2020	NOP receptor agonist attenuates nitroglycerin-induced migraine-like symptoms in mice.
1/2020	Acid-sensing ion channel 3 blockade inhibits durovascular and nitric oxide-mediated trigeminal pain.
1/2019	Delta opioid receptor agonists are effective for multiple types of headache disorders.
1/2018	Soluble guanylyl cyclase is a critical regulator of migraine-associated pain.
1/2018	Gene Network Dysregulation in the Trigeminal Ganglia and Nucleus Accumbens of a Model of Chronic Migraine-Associated Hyperalgesia.

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Amynah A Pradhan Research Topics

Disease

19	Migraine Disorders (Migraine) 01/2022 - 02/2014
15	Pain (Aches) 01/2022 - 10/2011
15	Hyperalgesia 10/2021 - 02/2014
6	Chronic Pain 01/2018 - 10/2011
4	Headache (Headaches) 01/2021 - 01/2017
3	Headache Disorders (Headache Syndromes) 10/2020 - 01/2019
2	Secondary Headache Disorders 10/2020 - 01/2019
2	Hypersensitivity (Allergy) 10/2016 - 05/2014
1	Epilepsy (Aura) 10/2020
1	Photophobia (Light Sensitivity) 01/2020
1	Post-Traumatic Headache 01/2019
1	Mood Disorders (Mood Disorder) 01/2018
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2017
1	Acute Pain 05/2014
1	Infections 07/2013
1	Vesicular Stomatitis 07/2013
1	Neuroblastoma 07/2013
1	Substance-Related Disorders (Drug Abuse) 10/2011
1	Disruptive, Impulse Control, and Conduct Disorders (Kleptomania) 10/2011
1	Brain Diseases (Brain Disorder) 10/2011

Drug/Important Bio-Agent (IBA)

15	Nitroglycerin (Dynamite)FDA LinkGeneric 01/2022 - 02/2014
10	delta Opioid Receptors (delta Opioid Receptor)IBA 01/2021 - 10/2011
9	Opioid Analgesics (Opioids)IBA 10/2021 - 10/2011
6	4- (alpha- (4- allyl- 2,5- dimethyl- 1- piperazinyl)- 3- methoxybenzyl)- N,N- diethylbenzamideIBA 01/2021 - 05/2014
5	Opioid Receptors (Opioid Receptor)IBA 01/2017 - 11/2012
4	Sumatriptan (Imigran)FDA LinkGeneric 01/2019 - 02/2014
3	Morphine (MS Contin)FDA LinkGeneric 10/2021 - 01/2017
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020 - 02/2014
3	NeuropeptidesIBA 12/2019 - 03/2015
2	Protein Isoforms (Isoforms)IBA 10/2021 - 01/2018
2	Calcitonin Gene-Related PeptideIBA 01/2021 - 12/2019
2	Tryptamines (Triptans)IBA 01/2020 - 01/2019
2	Topiramate (Topamax)FDA LinkGeneric 01/2018 - 02/2014
2	Propranolol (Inderal)FDA LinkGeneric 01/2018 - 10/2016
1	KNT 127IBA 01/2021
1	ConvulsantsIBA 01/2021
1	Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)IBA 01/2021
1	kappa Opioid Receptors (kappa Opioid Receptor)IBA 10/2020
1	Acid Sensing Ion ChannelsIBA 01/2020
1	Ro 64-6198IBA 01/2020
1	cis- 1- methyl- 7- ((4- (2,6- dichlorophenyl)piperidin- 1- yl)methyl)- 6,7,8,9- tetrahydro- 5H- benzocyclohepten- 5- olIBA 01/2020
1	Therapeutic UsesIBA 01/2020
1	ChromograninsIBA 12/2019
1	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA 12/2019
1	Peptides (Polypeptides)IBA 12/2019
1	Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA 12/2019
1	Vorinostat FDA Link 01/2019
1	Histone Deacetylase InhibitorsIBA 01/2019
1	Ethanol (Ethyl Alcohol)IBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2018
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2018
1	Peroxynitrous Acid (Peroxynitrite)IBA 01/2018
1	Soluble Guanylyl CyclaseIBA 01/2018
1	RNA (Ribonucleic Acid)IBA 01/2018
1	Memantine (Namenda)FDA Link 10/2016
1	Valproic Acid (Depakote)FDA LinkGeneric 10/2016
1	Amiloride (Midamor)FDA LinkGeneric 10/2016
1	beta-Arrestin 1IBA 03/2016
1	Substance PIBA 03/2015
1	Analgesics (Analgesic Drugs)IBA 03/2015
1	9- (8- azabicyclo(3.2.1)oct- 3- ylidene)- 9H- xanthene- 3- carboxylic acid diethylamideIBA 05/2014
1	Anti-Anxiety Agents (Anxiolytics)IBA 05/2014
1	Antidepressive Agents (Antidepressants)IBA 05/2014
1	Phosphodiesterase 5 InhibitorsIBA 02/2014
1	Sildenafil Citrate (Viagra)FDA Link 02/2014
1	Cre recombinaseIBA 07/2013
1	Green Fluorescent ProteinsIBA 07/2013
1	GTP-Binding Proteins (G-Protein)IBA 07/2013

Therapy/Procedure

9	Therapeutics 01/2021 - 02/2014
2	Drug Therapy (Chemotherapy) 01/2022 - 01/2021
2	Pain Management 10/2020 - 01/2017